Rejuran Won't Fix Deep Folds or Volume Loss
Rejuran Won't Fix Deep Folds or Volume Loss
Rejuran Won't Fix Deep Folds or Volume Loss
Fine lines and rough texture usually improve over 3–4 sessions, but sunken folds need something else. Here's how to tell which case you're in.
What You Must Know Before Getting Rejuran in Seoul
Hello.
I'm Dr. Wi Young-jin, a specialist at Beautystone Clinic.
One question I get asked all the time is,
"What does Rejuran actually do?"
There's no shortage of content out there,
but finding truly useful information? That's a different story.
Check out these posts too!
✦ Related Reading
For those searching for Rejuran
in Seoul — especially around Hongdae and the surrounding area —
here's what I've learned from 5 years of clinical experience.
Rejuran, PN, HA: Ingredients & Treatment Overview
Medical papers can be dense, right?
Let me break down two key studies for you.
This study isn't the highest level of evidence,
reducing wrinkles, improving skin texture, and enhancing elasticity, with statistically significant results in several studies
In short: fewer wrinkles, smoother texture, and firmer skin.
Rejuran Healer, PN 20mg/ml
Increased skin thickness,
reduced wrinkles,
improved skin texture
In a randomized split-face trial of 27 participants, the PN-treated side showed significantly higher GAIS scores at week 16 compared to HA filler, and greater reduction in skin roughness by week 28.
1. Know Exactly What Rejuran Is Before You Get It
Rejuran
is a polynucleotide (PN) extracted from salmon,
It's injected directly into the skin.
Simply put, it contains the building blocks of cells —
fragments of DNA.
So what does it actually do?
Anti-inflammation & regeneration.
PN stimulates collagen synthesis and promotes new blood vessel formation.
Improves aging signs and fine lines.
Collagen synthesis fills in fine lines and minimizes pores — anti-aging effect.
Improves depressed acne scars (cell regeneration).
Collagen fills in sunken scar areas, gradually lifting them up.
Restores skin barrier + reduces sensitivity.
Damaged skin barrier regenerates, bringing sensitive skin back to its normal state.
✔ This is not a volume-filling treatment like filler,
✔ nor does it affect muscles like Botox.
It works by helping skin cells produce collagen on their own —
which is why results look natural.
Many patients in Seoul ask about Rejuran:
"Will I see a big difference after just one session?"
Honestly speaking,
rather than dramatic changes,
think of it this way: 2. Who is it most effective for?They absorb naturally on their own.
In my clinical experience,
there are certain skin types that respond especially well to Rejuran 👇
✔ Rough skin texture and enlarged pores from severe acne in younger years
✔ Fine lines from thinning skin
✔ Overall loss of elasticity
Satisfaction tends to be high in these cases.
On the other hand,
❗ Deep nasolabial folds
❗ Significant volume loss
For these concerns,
Rejuran alone isn't the right choice.
In those cases,
combining filler or other treatments is recommended.
Based on patients visiting our clinic in Seoul,
"Is something wrong with my skin at this age?"
tend to report the highest satisfaction.
Late 30s to early 50s
No skin concerns? Rejuran may not be necessary.
Rejuran HB is a great option though → for a glass-skin glow effect.
📊 Rejuran Suitability Summary
Concern
Suitability | Notes | Fine lines / Uneven skin texture |
|---|---|---|
✅ Suitable | Effective after 3–4 sessions | Enlarged pores |
✅ Suitable | Effective after 3–4 sessions | Deep nasolabial folds |
⚠️ Supplementary | Filler recommended alongside | Volume loss |
❌ Not suitable | Filler / lifting preferred | Skin tone improvement |
✅ Suitable | Effective after 3–4 sessions | 3. Important precautions before & after treatment |
Rejuran is performed
with numbing cream applied beforehand.
👉 Treatment time is approximately 30 minutes.
After the procedure,
🔺 small bump-like papules may appear
🔺 for about 1–3 days.
This is not a side effect —
it's simply PN settling into the skin,
a normal response. 📌 Post-treatment precautionsThey absorb naturally on their own.
✔ Avoid cleansing and makeup on the day of treatment
✔ No intense exercise
✔ Limit alcohol consumption
📌 Duration of results
👉 Average 6–12 months
👉 After 3–4 sessions spaced 2–4 weeks apart,
maintenance sessions are recommended.
Some patients coming from the Hongdae area say,
"I had one session and didn't notice any difference."
This is something we hear from time to time.
Rejuran is
A treatment where results compound over time😊
Frequently Asked Questions (FAQ)
Q1. Why does Rejuran pricing vary by clinic?
A. Rejuran is a non-covered procedure, so pricing differs between clinics.
✔ Product type (Healer / Eye, etc.)
✔ Treatment area
✔ Doctor's experience
These factors all affect the price.
Also,
Whether the procedure is performed directly by the doctoris another key difference.
At Beautystone Clinic,
we provide transparent pricing during consultation.
Q2. Does Rejuran hurt?
A. We apply numbing cream beforehand,
so most patients find it very manageable.
There's a mild stinging sensation, but
✔ the procedure is quick
✔ and intensity can be adjusted,
so discomfort is minimal.
If you have sensitive skin,
just let us know 🙂
Q3. Can I combine Rejuran with fillers or Botox?
A. Yes, combination treatments are possible.
They can actually enhance each other's results.
However, too many procedures in one visit can be taxing,
so it's best to tailor the combination
to your skin condition.
If you're considering Rejuran in Seoul,
what matters most is
a plan designed for your skin.
At Beautystone Clinic in Hongdae,
✔ I personally handle every consultation
✔ and perform every procedure myself
We're also open on Sundays,
so if your schedule is tight,
feel free to visit anytime 🙌
Related post: 5 Safety Checklists to Prevent Accidents During Ulthera Sedation | Ulthera Results: How Many Shots Does It Take to See a Difference?
What You Must Know Before Getting Rejuran in Seoul
Hello.
I'm Dr. Wi Young-jin, a specialist at Beautystone Clinic.
One question I get asked all the time is,
"What does Rejuran actually do?"
There's no shortage of content out there,
but finding truly useful information? That's a different story.
Check out these posts too!
✦ Related Reading
For those searching for Rejuran
in Seoul — especially around Hongdae and the surrounding area —
here's what I've learned from 5 years of clinical experience.
Rejuran, PN, HA: Ingredients & Treatment Overview
Medical papers can be dense, right?
Let me break down two key studies for you.
This study isn't the highest level of evidence,
reducing wrinkles, improving skin texture, and enhancing elasticity, with statistically significant results in several studies
In short: fewer wrinkles, smoother texture, and firmer skin.
Rejuran Healer, PN 20mg/ml
Increased skin thickness,
reduced wrinkles,
improved skin texture
In a randomized split-face trial of 27 participants, the PN-treated side showed significantly higher GAIS scores at week 16 compared to HA filler, and greater reduction in skin roughness by week 28.
1. Know Exactly What Rejuran Is Before You Get It
Rejuran
is a polynucleotide (PN) extracted from salmon,
It's injected directly into the skin.
Simply put, it contains the building blocks of cells —
fragments of DNA.
So what does it actually do?
Anti-inflammation & regeneration.
PN stimulates collagen synthesis and promotes new blood vessel formation.
Improves aging signs and fine lines.
Collagen synthesis fills in fine lines and minimizes pores — anti-aging effect.
Improves depressed acne scars (cell regeneration).
Collagen fills in sunken scar areas, gradually lifting them up.
Restores skin barrier + reduces sensitivity.
Damaged skin barrier regenerates, bringing sensitive skin back to its normal state.
✔ This is not a volume-filling treatment like filler,
✔ nor does it affect muscles like Botox.
It works by helping skin cells produce collagen on their own —
which is why results look natural.
Many patients in Seoul ask about Rejuran:
"Will I see a big difference after just one session?"
Honestly speaking,
rather than dramatic changes,
think of it this way: 2. Who is it most effective for?They absorb naturally on their own.
In my clinical experience,
there are certain skin types that respond especially well to Rejuran 👇
✔ Rough skin texture and enlarged pores from severe acne in younger years
✔ Fine lines from thinning skin
✔ Overall loss of elasticity
Satisfaction tends to be high in these cases.
On the other hand,
❗ Deep nasolabial folds
❗ Significant volume loss
For these concerns,
Rejuran alone isn't the right choice.
In those cases,
combining filler or other treatments is recommended.
Based on patients visiting our clinic in Seoul,
"Is something wrong with my skin at this age?"
tend to report the highest satisfaction.
Late 30s to early 50s
No skin concerns? Rejuran may not be necessary.
Rejuran HB is a great option though → for a glass-skin glow effect.
📊 Rejuran Suitability Summary
Concern
Suitability | Notes | Fine lines / Uneven skin texture |
|---|---|---|
✅ Suitable | Effective after 3–4 sessions | Enlarged pores |
✅ Suitable | Effective after 3–4 sessions | Deep nasolabial folds |
⚠️ Supplementary | Filler recommended alongside | Volume loss |
❌ Not suitable | Filler / lifting preferred | Skin tone improvement |
✅ Suitable | Effective after 3–4 sessions | 3. Important precautions before & after treatment |
Rejuran is performed
with numbing cream applied beforehand.
👉 Treatment time is approximately 30 minutes.
After the procedure,
🔺 small bump-like papules may appear
🔺 for about 1–3 days.
This is not a side effect —
it's simply PN settling into the skin,
a normal response. 📌 Post-treatment precautionsThey absorb naturally on their own.
✔ Avoid cleansing and makeup on the day of treatment
✔ No intense exercise
✔ Limit alcohol consumption
📌 Duration of results
👉 Average 6–12 months
👉 After 3–4 sessions spaced 2–4 weeks apart,
maintenance sessions are recommended.
Some patients coming from the Hongdae area say,
"I had one session and didn't notice any difference."
This is something we hear from time to time.
Rejuran is
A treatment where results compound over time😊
Frequently Asked Questions (FAQ)
Q1. Why does Rejuran pricing vary by clinic?
A. Rejuran is a non-covered procedure, so pricing differs between clinics.
✔ Product type (Healer / Eye, etc.)
✔ Treatment area
✔ Doctor's experience
These factors all affect the price.
Also,
Whether the procedure is performed directly by the doctoris another key difference.
At Beautystone Clinic,
we provide transparent pricing during consultation.
Q2. Does Rejuran hurt?
A. We apply numbing cream beforehand,
so most patients find it very manageable.
There's a mild stinging sensation, but
✔ the procedure is quick
✔ and intensity can be adjusted,
so discomfort is minimal.
If you have sensitive skin,
just let us know 🙂
Q3. Can I combine Rejuran with fillers or Botox?
A. Yes, combination treatments are possible.
They can actually enhance each other's results.
However, too many procedures in one visit can be taxing,
so it's best to tailor the combination
to your skin condition.
If you're considering Rejuran in Seoul,
what matters most is
a plan designed for your skin.
At Beautystone Clinic in Hongdae,
✔ I personally handle every consultation
✔ and perform every procedure myself
We're also open on Sundays,
so if your schedule is tight,
feel free to visit anytime 🙌
Related post: 5 Safety Checklists to Prevent Accidents During Ulthera Sedation | Ulthera Results: How Many Shots Does It Take to See a Difference?
Latest post
Latest post
Lifting
Potenza Prep: When to Stop Retinol & Waxing
Booked a Potenza session? Here's a day-by-day countdown for pausing retinol, exfoliating acids, waxing, and self-tanner before your appointment.
Lifting
How Early to Book Oligio X Before an Event
Planning Oligio X around a wedding or a holiday photo? Here's how far ahead to book, what shows up at one week and one month, and when to wait.
skin
여름 지나 스킨부스터, 언제 시작하면 좋을까요
지금 피부가 회복 모드인지 자극 모드인지로 스킨부스터 시작 시점을 판단하는 방법과 상담 전 자가 점검 항목을 정리했어요.
skin
샤워와 세안 물 온도, 어느 정도가 좋을까요
뜨거운 물이 피지막에 어떻게 작용하는지부터 손등으로 미온수를 가늠하는 방법까지, 매일 반복되는 씻기 습관을 순서대로 정리했어요.
Lifting
Sofwave for Nasolabial Folds: What Changes
Nasolabial and marionette shadows come from loose skin, lost volume, or both. Here's how deep Sofwave works and when filler fits better.
Contouring & Volume
Sculptra for Hollow Temples: Session Planning
Wondering how many Sculptra sessions hollow temples need and how long to wait between them? Here's how the plan gets built, and when filler makes more sense.
1:1 Custom Approach
1:1 Consultation Whatsapp
🌸 Beautystone Clinic attends the Meditox Bangkok Cadaver Workshop 🌸
1:1 Custom Approach