Rejuran vs HB111: which filler suits your skin? A clinic director breaks down the real difference.
Rejuran Healer vs HB | How to Choose for Your Skin | Hongdae Beautystone Clinic
Hello, I'm Dr. Wi Young-jin, board-certified physician from Seoul National University College of Medicine and director of Beautystone Clinic.
So Rejuran is supposed to be great — but how many types are there?
Healer, HB, Eye, and S. Many people wonder if they're just different names or if they actually work differently. Today we break it all down — here's everything you need to know.
1. The Core Ingredient in Rejuran Is PN
PN stands for Polynucleotide.
Simply put, it's a precursor to DNA. It directly supports cell regeneration, giving it strong skin-healing properties.
When Rejuran first launched, it was used for burn patients and severely inflamed skin. Its use for cosmetic purposes in dermatology clinics is what we now call Rejuran Healer.
2. Healer vs HB — What's the Difference?
Rejuran Healer
PN only [20mg/ml]
Main benefits: cell regeneration, fine line improvement, inflammation recovery
Best for: compromised or inflamed skin
Fair warning — it hurts.
Rejuran HB
PN + Hyaluronic Acid (HA) [10mg/ml]
Combines regeneration (PN) with deep hydration (HA)
Best for: oily, dry, or dehydrated skin
Especially recommended for those with redness or rosacea
Contains lidocaine (numbing agent) — noticeably less painful
Rejuran Eye
PN only, formulated specifically for the eye area
Targets fine lines and dark circles around the eyes
3. Which One Should You Choose?
Acne or redness → HB (hydrates while calming inflammation)
Fine lines or cell regeneration → Healer
Dark circles or eye-area fine lines → Eye
Oily skin is often a sign of underlying dehydration. When skin lacks moisture, it overproduces sebum. That's exactly why HB tends to work so well for oily skin types.
4. How Many Sessions of Rejuran Do You Need?
For problem areas, 3 sessions spaced 4 weeks apart is the standard recommendation.
Even after effects fade, your skin won't fully revert to its previous state. With consistent treatment, collagen remodeling continues to occur. For Rejuran Eye in particular, long-term use can visibly reduce fine lines over time.
5. Treatments That Pair Well with Rejuran
Rejuran × Juvelook Skin Booster
While Rejuran's PN helps with regeneration and inflammation,
Juvelook's skin booster supports hydration and collagen production.
Make sure the injection depth isn't too shallow.
Learn More About Cellderma Re2O Human Allograft Dermis
Message us on KakaoTalk for a consultation.
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Beautystone Clinic is a 3-minute walk from Hapjeong Station. Open on Sundays.
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